Contaminants and Contamination

Contaminants

Any adventitiously introduced materials (e.g., chemical, biochemical, or microbial species) not intended to be part of the manufacturing process of the drug substance or drug product. (Reference: ICH Q6B).


Contamination

The undesired introduction of impurities of a chemical or microbiological nature, or of foreign matter, into or onto a raw material, intermediate, or Active Pharmaceutical Ingredient (API) during production, sampling, packaging or repackaging, storage or transport.


Related Topics:

Biodistribution (BD)ShockAntibiotic Stewardship
BioequivalenceBiotechnologyBioinformatics

Leave a Comment