Dissolution
Dissolution Vs. Disintegration: What is Right for your Product?
Dissolution and disintegration are both commonly used for checking the quality of solid oral dosage forms. While these two techniques ...
Dissolution and Dissolved Gasses: How Should You Handle Them?
Dissolved gasses in your dissolution media can cause a variety of issues to your run. If not controlled, these gasses ...
How Do You Choose an RPM in Dissolution?
I’ve seen a couple of “A.I. Slop” articles on LinkedIn this week about how to choose an RPM speed in ...
Does f2 Apply to Modified-Release Dissolution Profiles?
Short answer: Yes. But only if you meet the prerequisites Most of us learn f2 through immediate-release examples. That’s why ...
Is Coning Always a Problem?
One of the most common myths analysts come to me with is that coning is always a problem to be ...
Understanding Non-Sink Conditions in Dissolution Testing
In pharmaceutical R&D, dissolution testing plays a vital role in predicting drug release and bioavailability. While most studies are conducted ...
Discriminatory Dissolution & Q-Point Specification – The Connection
A dissolution method with discriminatory power ensures it can detect critical differences in formulation or process that may impact drug ...
The f2 Similarity Factor in Dissolution
One question that I frequently get about dissolution is what is the f2 factor and how should it be used? ...
Intrinsic Dissolution
In this chapter, we delve into the process of determining the intrinsic dissolution rate, a crucial factor in the characterization ...
Difference Between Dissolution and Disintegration
While both terms are fundamental to pharmaceutical development, they describe distinct processes that play critical roles in tablet performance and ...