Welcome to Pharma Topics Forums

The largest online community for industrial pharmacists.
Please or Register to create posts and topics.

Drug Layer Coating

How to optimize drug layer coating?

Which factors should consider for drug layer coating?

You should consider the below points for drug layer coating:

  • API solubility in coating solution
  • API stability in coating solution
  • Spray rate and wt. gain of the coating solution
  • Inlet and Bed temperature during spraying
Chief Pharmacist has reacted to this post.
Chief Pharmacist

How to reduce API loss in drug layer coating?

Optimum spray rate, inlet temperature and product temperature can reduce the loss of API during drug layer coating.

Drug-layer coating performed for which products?

Is there any alternative way to skip drug layer coating?

Drug-layer coating is usually performed for such products which are showed incompatibility in conventional process or for XR-IR combination products.

Bi-layer is an option but not for all products.