Blending in Pharmaceutical Manufacturing

Blending is defined as the process of combining materials within the same specification to produce a homogeneous intermediate or API.

In-process mixing of fractions from single batches (e.g., collecting several centrifuge loads from a single crystallization batch) or combining fractions from several batches for further processing is considered to be part of the production process and is not considered to be blending.

Common Types of Blending

  • Diffusion Blending (Tumble)
  • Convection Mixing
  • Pneumatic Mixing

Related Topics:

AuditCompressibility IndexAntibiotic Stewardship

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