Quote from Chief Pharmacist on October 1, 2024, 4:06 pm

As per FDA, the dissolution media selection should be based on formulation properties, solubility of the drug substance(s), and the stability of the drug substance(s) during the dissolution testing.

The media used in dissolution studies can include acidic or basic solutions, buffers, surfactants, and surfactants with acid or buffers.

Quote from ard on October 6, 2024, 9:42 am

Is there any reference article for detalis?

Please share...

Quote from Chief Pharmacist on October 6, 2024, 3:19 pm

You can see the below article:

https://www.pharmaspecialists.com/2021/09/selection-of-dissolution-medium-for-osd.html