Welcome to Pharma Topics Forums

The largest online community for industrial pharmacists.
Please or Register to create posts and topics.

Compression Problem

During compression we found weight variation of tablets. But previously such weight variation was not happened. What can be reason for this?

@sayeed

You should check the below points:

  • Granules size: for smaller tablet large granules and for larger tablet small granules may cause weight variation.
  • Granules flow: improper granules flow may cause weight variation. You should check it.