Disodium EDTA (ethylenediaminetetraacetic acid) is often used in eye drop preparations for its chelating properties, which help to stabilize formulations by binding metal ions.
Functions of Disodium EDTA in Eye Drops
- Preservative: It can help prevent the growth of bacteria and fungi in the solution.
- Stabilizer: By chelating metal ions, it helps to stabilize active ingredients and prevent degradation.
- Enhancer: It may enhance the penetration of other active ingredients through the corneal barrier.
Considerations
- Concentration: The concentration of disodium EDTA must be carefully controlled to ensure safety and efficacy. Typically, it is used in low concentrations.
- Compatibility: It’s important to consider the compatibility of disodium EDTA with other components in the formulation to avoid adverse reactions.
- Regulatory Approval: Formulations containing disodium EDTA should comply with regulatory standards set by health authorities.
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