Welcome to Pharma Topics Forums

The largest online community for industrial pharmacists.
Please or Register to create posts and topics.

PK Parameters for BE Study

Which pharmacokinetics parameters are considered in BE study?

Usually following parameters are measured in bioequivalence study:

  • AUC(0-t)
  • AUC(0-∞)
  • Cmax
  • tmax

Read details: https://www.pharmaspecialists.com/2024/01/bioequivalence-studies-for-solid-oral-drug-products.html

What is the impact of half-life in bioequivalence study? 

Half-life is useful for determining excretion rates as well as steady-state concentrations for any specific drug. It can influence how often you need to take a medication, how long it takes to work, and safety considerations, such as potential risks and interactions.

 

Refer to: https://www.pharmaspecialists.com/2024/11/role-of-half-life-and-tmax.html