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Dissolution Vessel Size
How many size of dissolution vessel used in pharmaceutical industry?
Dissolution vessels come in various sizes, although the standard size is 1 litre. Other available sizes range from 4 litres down to 100ml. The choice of vessel size depends on the specific testing requirements. Here are some typical uses for different vessel sizes:
- 4 Litre: These larger vessels find application in sample pooling and veterinary contexts, accommodating larger quantities of substances.
- 2 Litre: Ideal for testing low solubility drugs, the 2-litre vessel size allows for precise analysis in such cases.
- 1 Litre: The most commonly used size, the 1-litre vessel is versatile, suitable for a range of tests, including 100ml, 900ml, and 500ml tests.
- 500ml: Specifically designed for 500ml tests, ensuring accuracy in experiments with this particular volume.
- 350ml: Tailored for low dosage forms, the 350ml vessel may require specialized paddles to ensure proper dissolution, making it suitable for unique testing scenarios.
What is cone dissolution vessel and when it is required?
I think, you may want to know about peak vessel. It is used to overcome the coning problem arise during dissolution.
For details: https://www.pharmaspecialists.com/2023/10/coning-in-dissolution-vessels.html
